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It is not known whether this potentiation of ampicillin rashes is due to allopurinol or the hyperuricemia present in these patients. The total amount of allopurinol is usually not more than 800 mg a day. {07} {35} {36} Both allopurinol and the uricosuric antigout agents are effective in patients whose 24-hour renal excretion of uric acid is 800 mg (4. A reaction with another antigout drug, allopurinol, may cause a rash. {06} {35} {36} However, the uricosuric agents are less toxic than allopurinol and should be considered for use when appropriate {37}. There is no specific information comparing use of allopurinol in the elderly with use in other age groups.
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